Onycholysis occurs when the nail separates from the nail bed. This can result from certain medications or exposure to harsh chemicals, but it may also indicate thyroid dysfunction. Separation usually begins at the nail’s free edge and progresses toward the cuticle, forming a white or yellowish opaque area. Other potential causes include psoriasis, fungal infections, physical trauma, and specific medications like tetracycline antibiotics. Frequent manicures or prolonged water exposure can exacerbate the condition. Treatment varies based on the cause but often involves keeping the nails dry and clean, avoiding activities that aggravate the problem, and allowing the nail to regrow naturally. For cases related to systemic conditions such as thyroid disease, managing the underlying disorder is essential to prevent recurrence.
